PRELIMINARY PROGRAMME

 

Sunday
April 14
Monday
April 15
Tuesday
April 16
Wednesday
April 17
Thursday
April 18
Sunday
April 14
14.30-16.30 Registration Aula Magna. (Registration can also be made at the symposium desk when it is manned during the symposium.)
16.30-16.45 Opening and welcome
Plenary session
16.45-17.25 Large scale proteomics in medicine
Denis Hochstrasser, University of Geneva, Switzerland
17.25-18.05 Automated Nanoelectrospray Mass Spectrometry: A Chip-Based Strategy for High-Throughput Bioanalysis
Jack Henion, Cornell University, USA
18.05-18.15 Pause
18.15-18.55 Micro- and Nanofluidic Devices and Systems for a Lab-on-a-Chip
Albert van den Berg, University of Twente, The Netherlands
19.00-21.00 Buffet dinner at Stockholm University

 

Monday
April 15
 
  Proteomics I
09.00-09.30 High-Resolution Liquid Phase Separation Coupled to MALDI/TOF-MS for Proteomics
Barry Karger, Northeastern University, USA
09.30-09.50 The ProteinChip Approach to Proteomics: Protein Profiling and Biomarker Identification
Haleem Issaq, SAIC Frederick Inc, USA
09.50-10.10 On-line Coupling of Capillary Isoelectric Focusing with Transient Isotachophoresis/Zone Electophoresis: a Two-dimensional Separation System for Proteomics
Cheng Lee, University of Maryland, USA
10.10-10.30 Disposable Microchips for High Performance Protein Characterisation and Mass Spectrometric Proteome Analysis
Joel Rossier, DiagnoSwiss SA, Switzerland
10.30-11.00 Pause
11.00-12.30 Postersession
12.30-15.30 City Hall
  Proteomics II
15.30-16.00 Searching for Cancer Markers Through Comparative Proteomics
Fred Regnier, Purdue University, USA
16.00-16.20 Microtechnology Developments Applied to Proteomic Studies
György Marko-Varga, AstraZeneca R&D Lund, Sweden
16.20-16.40 High Throughput Proteomics with a 96-Capillary Instrument
Aran Paulus, Amersham Biosciences, USA
16.40-17.00

Peptide mapping of proteins in human body fluids using liquid based separations and FTICR-MS
Jonas Bergqvist, Uppsala University, Sweden

17.00-19.00 Postersession

 

Monday
April 15
 
  Biomedical I
09.00-09.30 Chiral Capillary Electrophoresis in Drug Bioanalysis
Wolfgang Thormann, University of Bern, Switzerland
09.30-09.50 Airborne Extraction CE/CEC & Nanospray-MS
Staffan Nilsson, Lund University, Sweden
09.50-10.10 Nonaqueous Capillary Electrophoresis - Mass Spectrometry: New Possibilities For UV Absorbing Solvents
Jean-Luc Veuthey, University of Geneva, Switzerland
10.10-10.30 The Analysis of Drugs of Forensic Interest by Capillary Electrophoresis using Dynamically Coated Capillaries Including Cyclodextrins
Ira Lurie, Special Testing and Research Laboratory, USA
10.30-11.00 Pause
11.00-12.30 Postersession
12.30-15.30 City Hall
  Fundamentals I
15.30-16.00 Chemical and Theoretical Toolbox for the Design and Preparation of New Matrices for Capillary and Microchannel Separations
Jean-Louis Viovy, Laboratoire de physico-chimie Curie, France
16.00-16.20

Microfluidic Devices for Two-Dimensional Separations
Stephen C. Jacobson, Oak Ridge National Laboratory, USA

16.20-16.40 Non Conventional Synthesis and Characterization of Ultra Large Polyacrylamides
Marcella Chiari, CNR, Italy
16.40-17.00 A high-throughput method for proteomics employing immunoaffinity capillary electrophoresis
Norberto A. Guzman, Johnson & Johnson Pharmaceutical Research and Development, U.S.A.
17.00-19.00 Postersession

 

Tuesday
April 16
 
  Proteomics III
09.00-09.30 Desorption/Ionization on Silicon (DIOS) Mass Spectrometry for Protein Characterization
Gary Siuzdak, The Scripps Research Institute, USA
09.30-09.50 Improving Capillary LC/MS(MS) Analysis for Proteomics
Steven Cohen, Waters Corporation, USA
09.50-10.10 High sensitivity proteome analysis using a combination of variable flow chromatography and ESI-MS/MS on a Q-Tof mass spectrometer
Hans Vissers, Micromass UK Ltd, UK
10.10-10.30 De novo sequencing of tryptic peptides using Chemically Assisted Fragmentation Matrix Assisted Laser Desorption Ionization (CAF-MALDI)
Maria Liminga, Amersham Biosciences, Sweden
10.30-11.00 Pause
11.00-12.30 Postersession
12.30-14.00 Lunch
   
  Tutorial lecture
13.00-13.45 Rapid Optimization of Electrophoretic Separations by Using Combinatorial Buffer Systems
Edward S Yeung, Iowa State University, USA
   
  Protein analysis I
14.00-14.30 Reduction and Alkylation of Proteins in Proteome Analysis: why, when and how?
Pier Giorgio Righetti, University of Verona, Italy
14.30-14.50 Laser-Polymerized Thin-Film Coating for Protein Analysis by Capillary Gel Electrophoresis in a Microchip
Julia Fruetel, Sandia National Laboratories, USA
14.50-15.10 If Zwitterionic Salts Don't Prevent Protein Adsorption, What Do They Do?
Charles Lucy, University of Alberta, Canada
15.10-15.30 Protein chip technology in research and clinical proteomics
Janne Lehtiö, Ciphergen Biosystems A/S, Sweden
15.30-16.00 Pause
  Protein analysis II
16.00-16.30 Characterization of Complex Biological Fluids Using Proteomics
Bill Hancock, ThermoFinnigan, USA
16.30-16.50 Adding Function to Protein Characterization by Microelectrophoretic Methods
Niels Heegaard, Statens Serum Institut, Denmark
16.50-17.10 Mobility-Moment Analysis of Protein-Protein Interactions
Kiyohito Shimura, Teikyo University, Japan
17.10-17.30 Correlation Between Capillary and Free-Flow Electrophoresis – Basis for Conversion of Analytical Separations of Biologically Active Peptides to Preparative Scale
Vaclav Kasicka, Czech Academy of Sciences, Czech Republic
19.30- Conference dinner

 

Tuesday
April 16
 
  Enantioseparations
09.00-09.30 Enantioseparations in Capillary Electromigration Techniques
Bezhan Chankvetadze, University of Münster, Germany
09.30-09.50 Microchip and Capillary Array Electrophoresis for Chiral High Throughput Screening
Detlev Belder, Max-Planck-Institut für Kohlenforschung, Germany
09.50-10.10 Capillary Electrochromatographic Enantioseparations Using Physically Adsorbed Avidin in Monolithic Silica and Open Tubular Capillaries
Koji Otsuka, Himeji Institute of Technology, Japan
10.10-10.30 Use of Glycopeptide Antibiotic Stationary Phase in Electrochromatography. MDL 63,246 (A Teicoplanin Derivative) for the Enantioresolution of Acidic Compounds
Salvatore Fanali, Istituto di Cromatografia del CNR, Italy
10.30-11.00 Pause
11.00-12.30 Postersession
12.30-14.00 Lunch
   
  Tutorial lecture
13.00-13.45 CE, CE-MS/MS and nanospray -MS/MS for clinical problem solving
Katja Elgstoen/ Egil Jellum, Rikshospitalet University Hospital, Norway
   
  Pharmaceutical analysis
14.00-14.20 Approaches to Development, Optimisation and Application of Routine CE Methods for Pharmaceutical Analysis
Kevin Altria, GlaxoSmithKline, UK
14.20-15.30 Short presentations from industrial representatives and plenary discussion about the role of electrodriven techniques in industry, with a focus on pharmaceutical analysis.
Co-chair:  Cari Sänger, AstraZeneca R&D Södertälje 
David Lloyd, Bristol-Myers Squibb Company, USA
Contributors:
Kevin Altria, GlaxoSmithKline, UK
Christian Korn, Aventis, Germany
Ilias Jimidar, Jansson Research Foundation, J&J, Belgium
Peter Wijnen and Joop Waterval, Organon, The Netherlands
Anders Engström, Biovitrum, Sweden
Roman Szucs, Pfizer, UK
Stacy Ma, Genentech, USA
Norberto Guzman, RW Johnson, USA
Michael Little, Boehringer-Ingelheim, Canada
Franka Kálmán, Solvias, Switzerland
15.30-16.00 Pause
16.00-17.30 Pharmaceutical analysis continue
19.30- Conference dinner

 

Wednesday
April 17
 
  Chip technology I
09.00-09.30 Circular separations and Fourier transform
Andreas Manz, Imperial College, UK
09.30-09.50 Novel Sample Handling Technologies in Micro- and Nano-scale Chemistry
Johan Roeraade, Royal Institute of Technology, Sweden
09.50-10.10 Isocratic and Gradient Electrochromatography Using Packed Beds On-a-Chip
Yolanda Fintschenko, Sandia National Laboratories, USA
10.10-10.30 Sub-second LC Separations by means of Shear-Driven Chromatography
Gert Desmet, Vrije Universiteit Brussel, Belgium
10.30-11.00 Pause
11.00-12.30 Postersession
12.30-14.00 Lunch
  Chip technology II
14.00-14.30

Integrated Bio and Chemical Systems -The Status Quo and the Second Stage
Takehiko Kitamori, University of Tokyo, Japan

14.30-14.50 Sample preparation on a CD for MALDI-MS analyses
Per Andersson, Gyros AB, Sweden
14.50-15.10 Single Cell Analysis on Microfluidic Devices Techniques
Christopher Culbertson, Oak Ridge National Laboratory, USA
15.10-15.30 Porous Polymer Monoliths for Fabrication of Analytical Microfluidic Systems
Frantisek Svec, University of California, USA
15.30-16.00 Pause
  Genomics
16.00-16.30 DNA Diagnostics on Microchip Platforms (tentative)
James P. Landers, University of Virginia, USA
16.30-16.50 Micropreparative Separation Methods
Andras Guttman, Torrey Mesa Research Institute, USA
16.50-17.10 Geometrical Electrophoresis Based on Micro- and Nano-Fabrication
Masanori Ueda, University of Tokushima, Japan
17.10-17.30 Critical Molecular Design Factors for the Performance of Dynamically Adsorbed, Polymeric Wall Coatings for Microchannel Electrophoresis
Annelise Barron, Northwestern University, USA
17.30-17.50 Detection of DNA Adducts by Dye Labelling CE-LIF/MS
Roger Giese, Northeastern University, USA

 

Wednesday
April 17
 
  CEC
09.00-09.30 Design of Monolithic Columns for Capillary HPLC and CEC
Nobuo Tanaka, Kyoto Institute of Technology, Japan
09.30-09.50 Determination of the Height Equivalent of a Theoretical Plate in Capillary Electrochromatography Systems Involving Intraparticle Fluid Flow
Athanasios Liapis, University of Missouri-Rlla, USA
09.50-10.10 Photopolymerized Sol-gel Monoliths as Preconcentrators and Separators in Capillary Electrochromatography
Maria Dulay, Stanford University, USA
10.10-10.30 Electrochromatography in Chips: Rversed-Phase Separation of Peptides and Amino Acids Using Polymer Monoliths Photopatterned in Channels of a Glass Microchip
Anup Singh, Sandia National Laboratories, USA
10.30-11.00 Pause
11.00-12.30 Postersession
12.30-14.00 Lunch
  Biomedical II
14.00-14.30 On-line Nanoliter-Volume NMR Detection for Capillary Separations
Jonathan V Sweedler, University of Illinois, USA
14.30-14.50 Biochemical Applications of CEC and CEC/MS-MS using Monolithic Columns
Milos V Novotny, Indiana University, USA
14.50-15.10 Towards Single Molecule Fluorescence Detection in Constricted Fused-Silica Capillaries
Anders Lundqvist, Göteborg University, Sweden
15.10-15.30 Capillary Electromigration Techniques and Liposomes
Marja-Liisa Riekkola, University of Helsinki, Finland
15.30-16.00 Pause
  Biomedical III
16.00-16.30 Affinity Interactions of Biological Macromolecular Assemblies - Viruses - With Neutralising Agents Quantified by Capillary Electrophoresis
Ernst Kenndler, University of Vienna, Austria
16.30-16.50 Capillary Electrophoresis of Bacteria and Bacterial Virulence Factors
Ferenc Kilar, University of Pécs, Hungary
16.50-17.10 Single Cell Diagnostics
Karel Kleparnik, Academy of Sciences of the Czech Republic, Czech Republic
17.10-17.30 Determination of Diadenosine Polyphosphates in Human Platelets by Capillary Electrophoresis
Gottfried Blaschke, University of Münster, Germany
17.30-17.50 Microchip-based Capillary Electrophoresis for Biomolecules Analysis
Bincheng Lin, Dalian Institute of Chemical Physics, China

 

Thursday
April 18
 
  Biomedical IV
09.00-09.30 The Challenge of Multivariate Metabolic Analysis in the Post-Genomic Era: Insights from NMR Spectroscopy and Chemometrics
Jeremy Nicholson, Imperial College, UK
09.30-09.50 Particle Counting and Sizing on Microfluidic Devices Based on Light Scattering
Nicole Pamme, Imperial College of STM, UK
09.50-10.10 High Throughput Preparation of Nanoscale Samples for a Microchip-Based Analysis System
Stevan Jovanovich, Amersham Biosciences, USA
10.10-10.30 A Competition Immunoassay That Detects The Abnormal Prion Protein in the Blood of Sheep Infected With Scrapie
Mary Jo Schmerr, National Animal Disease Center, USA
10.30-11.00 Pause
  MEKC
11.00-11.30 On-Line Sample Preconcentration Techniques for High Sensitivity Capillary Electrophoresis using Sweeping and Dynamic pH-Junction
Shigeru Terabe, Himeji Institute of Technology, Japan
11.30-11.50 Partial Filling Technique: Retention and Peak Area Artifacts Caused by Conductivity Variation
Gunnar Johansson, Uppsala University, Sweden
11.50-12.10 Moderation of the Electroosmotic Flow and its Consequences for the Separation Performance in (Micellar) Electrokinetic Chromatography
Thomas Welsch, University of Ulm, Germany
12.10-12.30 Modeling of Micellar Electrokinetic Chromatography Separations Using Theoretical Molecular Descriptors
Eivor Örnskov, Uppsala University, Sweden
12.30-14.00 Lunch

 

Thursday
April 18
 
  Fundamentals II
09.00-09.30 Molecular Transport through Nanoscale Fabricated Channels
J Michael Ramsey, Oak Ridge National Laboratory, USA
09.30-09.50 CZE and CGE of Synthetic Polymers
Heinz Engelhardt, University of the Saarland, Germany
09.50-10.10 Advanced Computational Tools for Predicting Behavior of Electrophoretic Systems
Bohuslav Gas, Charles University, Czech Republic
10.10-10.30 Design and evaluation of continuos beds for enentioseparations and bioanalysis
Audrius Maruska, Vytautas Magnus University
10.30-11.00 Pause
  Fundamentals III
11.00-11.30 Artificial Cells, and Cell Networks for Manipulation,Processing, and Detection of Single Molecules in Nanoscopic Domains
Owe Orvar, Göteborg University, Sweden
11.30-11.50 The Selectivity of "Artificial Antibodies", as Analyzed by Capillary Electrophoresis
Stellan Hjertén, Uppsala University, Sweden
11.50-12.10 Online Mid Infrared Detection in Capillary Based Systems
Bernhard Lendl, Vienna University of Technology, Austria
12.10-12.30 Zone Electrophoresis With On-Line Isotachophoresis Sample Pretreatment On a Chip
Dusan Kaniansky, Comenius University, Slovak Republic
  12.30-14.00 Lunch

 

Thursday
April 18
 
  Plenary session
14.00-14.40 Biomedical applications of capillary electrophoresis: the neurosciences
Robert Kennedy, University of Florida, USA
14.40-15.20 Analytical screening technologies for drug discovery based on the integration of LC-MS and biochemical assays
Hubertus Irth, Vrije Universiteit Amsterdam, The Netherlands
15.20-16.00 Genomics (tentative)
Matthias Uhlén, Royal Institute of Technology, Sweden
16.00-16.10 Invitation to HPCE 2003, San Diego, USA
Aran Paulus and Andras Guttman
16.10-16.20 Invitation to HPCE 2004, Salzburg, Austria
Wolfgang Lindner
16.20-17.00 Farewell party