Trends in Organic Chemistry

The search for biologically active agents with therapeutic value has occupied mankind for thousands of years. Medicinal chemistry today concerns the discovery and development of biologically active compounds as well as the interpretation of their mode of action on a molecular level. In addition to the potential for drug development biologically active compounds can also be used as chemical tools to study biological systems in health and disease. Modern medicinal chemistry relies on a number of techniques including synthetic organic chemistry, structure-based approaches and computational chemistry. In this Symposium different topics in medicinal chemistry will be presented and discussed.

The symposium forms part of the series ”Trends in Organic Chemistry” sponsored by the Swedish Chemical Society Division of Organic Chemistry.

Programme:
09.30-09.50	Coffee
09.50-10.00	Welcome
10.00-11.00	William L. Jorgensen, Yale University, New Haven, USA Success story - Computer-aided design for anti-HIV agents
11.00-12.00	Paul Knochel, Ludwig-Maximilians-Universität, Munich, Germany New preparations of functionalized Grignard-reagents
12.00-13.00	Lunch
13.00-14.00	David Rees, Astex Therapeutics Ltd, Cambridge, UK Drug discovery – From fragment chemistry to clinic
14.00-15.00	Jon Clardy, Harvard Medical School, Boston, USA Discovering new compounds in nature
15.00-15.30	Coffee
15.30-16.30	Scott Sieburth, Temple University, Philadelphia, USA Silicon as a central drug design element
16.30-17.30	Jin Li, AstraZeneca Mölndal, Sweden Exploiting computational and informatics resources for GPCR ligand design

Participation in the scientific programme is free of charge. Lunch and coffee in the morning and afternoon will be provided for SEK 95. Please register participation in the programme and lunch by e-mail to johanna@chemsoc.se, no later than March 20, 2006.

Symposium hosts: Fredrik Almqvist, Mikael Elofsson and Anna Linusson, Organic Chemistry, Umeå University.

For further information contact symposium host Fredrik Almqvist, e-mail: fredrik.almqvist@chem.umu.se.

Location: Lecture hall KB3A9, KBC, Umeå University (link to map)

“Trends” symposium series sponsor: AstraZeneca R&D.

Sponsors, this symposium:	Biotech Umeå
	FOI Umeå
	Innate Pharmaceuticals AB
	SeQuant AB
	Swedish Research Council
	Umetrics AB